Donald Lavelle : rechercher sur Z-Library

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1

Histone deacetylase inhibitors increase p21WAF1 and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression

Donald Lavelle, Yi-Hsiang Chen, Maria Hankewych, Joseph DeSimone

Journal:

American Journal of Hematology

Année:

2001

Langue:

english

Fichier:

PDF, 685 KB

english, 2001

2

Oral decitabine reactivates expression of the methylated γ-globin gene in Papio anubis

Donald Lavelle, Janet Chin, Kestis Vaitkus, Sanjeev Redkar, Pasit Phiasivongsa, Chunlin Tang, Roselle Will, Maria Hankewych, Bryan Roxas, Mahipal Singh, Yogen Saunthararajah, Joseph DeSimone

Journal:

American Journal of Hematology

Année:

2007

Langue:

english

Fichier:

PDF, 223 KB

english, 2007

3

Fetal hemoglobin reactivation in baboon and man: A short perspective

Donald Lavelle, Joseph Desimone, Paul Heller

Journal:

American Journal of Hematology

Année:

1993

Langue:

english

Fichier:

PDF, 516 KB

english, 1993

4

Increased binding of SP1 to the γ-globin gene promoter upon site-specific cytosine methylation

Pritam K. Sengupta, Donald Lavelle, Dr. Joseph Desimone

Journal:

American Journal of Hematology

Année:

1994

Langue:

english

Fichier:

PDF, 400 KB

english, 1994

5

Decitabine induces cell cycle arrest at the G1 phase via p21WAF1 and the G2/M phase via the p38 MAP kinase pathway

Donald Lavelle, Joseph DeSimone, Maria Hankewych, Tatiana Kousnetzova, Yi-Hsiang Chen

Journal:

Leukemia Research

Année:

2003

Langue:

english

Fichier:

PDF, 374 KB

english, 2003

6

DNA hypo-methylating agents and sickle cell disease

Yogen Saunthararajah, Donald Lavelle, Joseph DeSimone

Journal:

British Journal of Haematology

Année:

2004

Langue:

english

Fichier:

PDF, 252 KB

english, 2004

7

Clinical effectiveness of decitabine in severe sickle cell disease

Yogen Saunthararajah, Robert Molokie, Santosh Saraf, Seema Sidhwani, Michel Gowhari, Steven Vara, Donald Lavelle, Joseph DeSimone

Journal:

British Journal of Haematology

Année:

2008

Langue:

english

Fichier:

PDF, 176 KB

english, 2008

8

Standard clinical practice underestimates the role and significance of erythropoietin deficiency in sickle cell disease

Santosh Saraf, Mohammed Farooqui, Giovanni Infusino, Bharvi Oza, Seema Sidhwani, Michel Gowhari, Stephen Vara, Weihua Gao, Lani Krauz, Donald Lavelle, Joseph DeSimone, Robert Molokie, Yogen Sauntharar

Journal:

British Journal of Haematology

Année:

2011

Langue:

english

Fichier:

PDF, 164 KB

english, 2011

9

Effect of 5-aza-2′-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the ɛ-, γ-, and β-globin promoters in Papio anubis

Donald Lavelle, Kestis Vaitkus, Maria Hankewych, Mahipal Singh, Joseph DeSimone

Journal:

Experimental Hematology

Année:

2006

Langue:

english

Fichier:

PDF, 276 KB

english, 2006

10

The γ-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow

Mahipal Singh, Donald Lavelle, Kestis Vaitkus, Nadim Mahmud, Maria Hankewych, Joseph DeSimone

Journal:

Experimental Hematology

Année:

2007

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2007

11

Transcriptional activation of the γ-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms

Janet Chin, Mahipal Singh, Virryan Banzon, Kestis Vaitkus, Vinzon Ibanez, Tatiana Kouznetsova, Nadim Mahmud, Joseph DeSimone, Donald Lavelle

Journal:

Experimental Hematology

Année:

2009

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2009

12

Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues

Hiroto Araki, Sudhakar Baluchamy, Kazumi Yoshinaga, Benjamin Petro, Sakina Petiwala, Ritesh Parajuli, Mohammed Milhem, Donald Lavelle, Joseph DeSimone, Nadim Mahmud

Journal:

Experimental Hematology

Année:

2009

Langue:

english

Fichier:

PDF, 637 KB

english, 2009

13

siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)−dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures

Virryan Banzon, Vinzon Ibanez, Kestis Vaitkus, Maria Armila Ruiz, Kenneth Peterson, Joseph DeSimone, Donald Lavelle

Journal:

Experimental Hematology

Année:

2011

Langue:

english

Fichier:

PDF, 864 KB

english, 2011

14

Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription

Imo Akpan, Virryan Banzon, Vinzon Ibanez, Kestis Vaitkus, Joseph DeSimone, Donald Lavelle

Journal:

Experimental Hematology

Année:

2010

Langue:

english

Fichier:

PDF, 173 KB

english, 2010

15

Effects of hydroxurea, stem cell factor, and erythropoietin in combination on fetal hemoglobin in the baboon

Donald Lavelle, Robert Molokie, Janice Ducksworth, Joseph DeSimone

Journal:

Experimental Hematology

Année:

2001

Langue:

english

Fichier:

PDF, 153 KB

english, 2001

16

Developmental changes in DNA methylation and covalent histone modifications of chromatin associated with the ε-, γ-, and β-globin gene promoters in Papio anubis

Donald Lavelle, Kestis Vaitkus, Maria Hankewych, Mahipal Singh, Joseph DeSimone

Journal:

Blood Cells, Molecules, and Diseases

Année:

2006

Langue:

english

Fichier:

PDF, 608 KB

english, 2006

17

Oral decitabine reactivates fetal hemoglobin in baboons (Papio anubis)

Donald Lavelle, Janet Chin, Kestis Vaitkus, Sanjeev Redkar, Pasit Phiasivongsa, Chunlin Tang, Roselle Will, Maria Hankewych, Mahipal Singh, Yogen Sauthararajah, Joseph DeSimone

Journal:

Blood Cells, Molecules, and Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 58 KB

english, 2007

18

Recapitulation of the fetal pattern of expression of the Iγ- and Vγ-globin genes in cultured baboon CD34+ bone marrow cells

Donald Lavelle, Kestis Vaitkus, Joseph DeSimone

Journal:

Blood Cells, Molecules, and Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 69 KB

english, 2007

19

The pattern of covalent histone modifications throughout the β-globin gene locus in fetal liver and adult bone marrow erythroblasts pre- and post-decitabine

Donald Lavelle, Janet Chin, Kestis Vaitkus, Mahipal Singh, Maria Hankewych, Joseph DeSimone

Journal:

Blood Cells, Molecules, and Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 57 KB

english, 2007

20

Regulation of myeloma cell growth through Akt/Gsk3/forkhead signaling pathway

Maaza G-Amlak, Shahab Uddin, Dolores Mahmud, Ingrid Damacela, Donald Lavelle, Maqbool Ahmed, Koen van Besien, Amittha Wickrema

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 186 KB

english, 2002

21

The molecular mechanism of fetal hemoglobin reactivation

Donald E. Lavelle

Journal:

Seminars in Hematology

Année:

2004

Langue:

english

Fichier:

PDF, 315 KB

english, 2004

22

Cost-effectiveness of distal embolic protection for patients undergoing percutaneous intervention of saphenous vein bypass grafts: Results from the SAFER trial

David J. Cohen, Sabina A. Murphy, Donald S. Baim, Tara A. Lavelle, Ronna H. Berezin, Donald E. Cutlip, Kalon K.L. Ho, Richard E. Kuntz

Journal:

Journal of the American College of Cardiology

Année:

2004

Langue:

english

Fichier:

PDF, 129 KB

english, 2004

23

S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)

Donald Lavelle, Yogen Saunthararajah, Kestis Vaitkus, Mahipal Singh, Virryan Banzon, Pasit Phiasivongsva, Sanjeev Redkar, Sarath Kanekal, David Bearss, Chongtie Shi, Roger Inloes, Joseph DeSimone

Journal:

Journal of Translational Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2010

24

EFFECTS OF VITAMIN D (CALCITRIOL) ON TRANSITIONAL CELL CARCINOMA OF THE BLADDER IN VITRO AND IN VIVO

KONETY, BADRINATH R., LAVELLE, JOHN P., PIRTSKALAISHVILI, GIORGI, DHIR, RAJIV, MEYERS, SUSAN A., NGUYEN, THU-SUONG T., HERSHBERGER, PAMELA, SHURIN, MICHAEL R., JOHNSON, CANDACE S., TRUMP, DONALD L., Z

Journal:

The Journal of Urology

Année:

2001

Langue:

english

Fichier:

PDF, 613 KB

english, 2001

25

Differential Effects of Epigenetic Modifiers on the Expansion and Maintenance of Human Cord Blood Stem/Progenitor Cells

Mahmud, Nadim, Petro, Benjamin, Baluchamy, Sudhakar, Li, Xinmin, Taioli, Simona, Lavelle, Donald, Quigley, John G., Suphangul, Montha, Araki, Hiroto

Journal:

Biology of Blood and Marrow Transplantation

Année:

2014

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2014

26

A Simple Method of Maintaining Chronic Vascular Access in the Dog

Endres, Donald R., Akimoto, Yoichi, Lavelle-Jones, Michael, Wahlstrom, H. Erik

Journal:

Journal of Investigative Surgery

Année:

1990

Langue:

english

Fichier:

PDF, 812 KB

english, 1990

27

Summary of Symposium on Dental Perspectives—International Year of the Child

Lavelle, Christopher L.B., Lewis, Donald W., Beagrie, George S.

Journal:

Journal of the American Dental Association

Année:

1980

Langue:

english

Fichier:

PDF, 1.62 MB

english, 1980

28

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

Ruiz, Maria Armila, Rivers, Angela, Ibanez, Vinzon, Vaitkus, Kestis, Mahmud, Nadim, DeSimone, Joseph, Lavelle, Donald

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2015

29

RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model

Rivers, Angela, Vaitkus, Kestis, Ruiz, Maria Armila, Ibanez, Vinzon, Jagadeeswaran, Ramasamy, Kouznetsova, Tatiana, DeSimone, Joseph, Lavelle, Donald

Journal:

Experimental Hematology

Année:

2015

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2015

30

Prophylaxis against Disseminated Mycobacterium avium Complex with Weekly Azithromycin, Daily Rifabutin, or Both

Havlir, Diane V., Dubé, Michael P., Sattler, Fred R., Forthal, Donald N., Kemper, Carol A., Dunne, Michael W., Parenti, David M., Lavelle, James P., White, A. Clinton, Witt, Mallory D., Bozzette, Samu

Journal:

Boston Medical and Surgical Journal

Année:

1996

Langue:

english

Fichier:

PDF, 114 KB

english, 1996

31

A Homeodomain Protein Binds to γ-Globin Gene Regulatory Sequences

Donald Lavelle, Janice Ducksworth, Eva Eves, Georgina Gomes, Michael Keller, Paul Heller and Joseph DeSimone

Journal:

Proceedings of the National Academy of Sciences

Année:

1991

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1991

32

Inhibition of Myeloma Cell Growth by All -Trans Retinoic Acid is Associated with Upregulatidn of p21 and Dephosphorylation of the Retinoblastoma Protein

Lavelle, Donald, Chen, Yi-Hsiang, Hankewych, Maria, Desimone, Joseph

Journal:

Leukemia and Lymphoma

Année:

1999

Langue:

english

Fichier:

PDF, 863 KB

english, 1999

33

Modulation of Interleukin-6/Interleukin-6 Receptor Cytokine Loop in the Treatment of Multiple Myeloma

Chen, Yi-Hsiang, Shiao, Rei-Tsang, Labayog, Jo-Mel, Modi, Sanjiv, Lavelle, Donald

Journal:

Leukemia and Lymphoma

Année:

1997

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1997

34

A Streamlined Pharynx Airway Liner: A Pilot Study in 22 Patients in Controlled and Spontaneous Ventilation

M. Miller, Donald, Lavelle, Margie

Journal:

Anesthesia & Analgesia

Année:

2002

Langue:

english

Fichier:

PDF, 59 KB

english, 2002

35

Pharmacokinetics of Oral Ganciclovir Alone and in Combination With Zidovudine, Didanosine, and Probenecid in HIV-Infected Subjects

Cimoch, Paul J., Lavelle, James, Pollard, Richard, Griffy, Kay Gaines, Wong, Rodney, Tarnowski, Thomas L., Casserella, Sandra, Jung, Donald

Journal:

Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology

Année:

1998

Fichier:

PDF, 5.08 MB

1998

36

Long-Term Physiologic Consequences of the Adult Respiratory Distress Syndrome.

Rotman, Harold H., Lavelle, Thomas F., Dimcheff, Donald G., VandenBelt, R.J., Weg, John G.

Journal:

Année:

1977

Langue:

english

Fichier:

PDF, 1.55 MB

english, 1977

37

[Offshore Technology Conference Offshore Technology Conference - Houston, Texas (1973-04-28)] Offshore Technology Conference - NOAATs Atlantic Margin Sediment Flux Study

Freeland, George L., Swift, Donald J.P., Keller, George H., Lavelle, J. William

Langue:

english

Fichier:

PDF, 503 KB

english

38

Effect of Food on the Relative Bioavailability of Oral Ganciclovir

Lavelle, James, Follansbee, Stephen, Trapnell, Carol B., Buhles, William C., Griffy, Kay Gaines, Jung, Donald, Dorr, Albert, Connor, James

Journal:

Journal of Clinical Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 530 KB

english, 1996

39

Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons

Ibanez, Vinzon, Vaitkus, Kestis, Rivers, Angela, Molokie, Robert, Cui, Shuaiying, Engel, James Douglas, DeSimone, Joseph, Lavelle, Donald

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 652 KB

english, 2017

40

Fetal Hemoglobin Induction by Epigenetic Drugs

Lavelle, Donald, Engel, James Douglas, Saunthararajah, Yogen

Journal:

Seminars in Hematology

Année:

2018

Langue:

english

Fichier:

PDF, 938 KB

english, 2018

41

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study

Molokie, Robert, Lavelle, Donald, Gowhari, Michel, Pacini, Michael, Krauz, Lani, Hassan, Johara, Ibanez, Vinzon, Ruiz, Maria A., Ng, Kwok Peng, Woost, Philip, Radivoyevitch, Tomas, Pacelli, Daisy, Fad

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 15.21 MB

english, 2017

42

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors

Lavelle, Donald, Vaitkus, Kestutis, Ruiz, Maria Armila, Ibanez, Vinzon, Kouznetsova, Tatiana, Saunthararajah, Yogen, Mahmud, Nadim, DeSimone, Joseph, Ivanovic, Zoran

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2012

43

The potential role of LSD1 inhibitors in the treatment of sickle cell disease: A review of preclinical animal model data

Rivers, Angela, Jagadeeswaran, Ramasamy, Lavelle, Donald

Journal:

American Journal of Physiology. Regulatory, Integrative and Comparative Physiology

Année:

2018

Langue:

english

Fichier:

PDF, 969 KB

english, 2018

44

Growth Inhibition of a Human Myeloma Cell Line by All-transRetinoic Acid Is Not Mediated Through Downregulation of Interleukin-6 Receptors but Through Upregulation of p21WAF1

Chen, Yi-Hsiang, Lavelle, Donald, DeSimone, Joseph, Uddin, Shahab, Platanias, Leonidas C., Hankewych, Maria

Journal:

Année:

1999

Fichier:

PDF, 256 KB

1999

45

2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia

Koshy, Mabel, Dorn, Louise, Bressler, Linda, Molokie, Robert, Lavelle, Donald, Talischy, Nasrin, Hoffman, Ronald, van Overveld, Wendy, DeSimone, Joseph

Journal:

Année:

2000

Fichier:

PDF, 183 KB

2000

46

A new target for fetal hemoglobin reactivation

Rivers, Angela, Molokie, Robert, Lavelle, Donald

Journal:

Année:

2019

Fichier:

PDF, 376 KB

2019

47

The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with Î²-Hemoglobin Disorders

Chambers, Christopher B., Gross, Jeffrey, Pratt, Katherine, Guo, Xiang, Byrnes, Colleen, Lee, Y. Terry, Lavelle, Donald, Dean, Ann, Miller, Jeffery L., Wilber, Andrew

Journal:

Molecular Therapy — Methods & Clinical Development

Année:

2020

Fichier:

PDF, 1.62 MB

2020